Lovastatin Hydroxy Acid, Sodium Salt

Name	Lovastatin Hydroxy Acid, Sodium Salt
Synonyms	MB 530B LOVASTATIN SODIUM sodium mevinolinate LOVASTATIN SODIUM SALT Lovastatin Hydroxy Acid Lovastatin EP IMpurity B LOVASTATIN HYDROXY ACID, SODIUM SALT Lovastatin Hydroxy Acid, Sodium Salt sodium (3R,5R)-7-[(1S,2S,6R,8S,8aR)-2,6-dimethyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate [1s-[1a(bs,ds),2a,6b,8b(r),8aa]]-1,2,6,7,8,8a-hexahydro-b,d-dihydroxy-2,6-dimethyl-8-(2-methyl-1-oxobutoxy)-1-naphthaleneheptanoic acid monosodium salt
CAS	75225-50-2
InChI	InChI=1/C24H38O6.Na/c1-5-15(3)24(29)30-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-18(25)12-19(26)13-22(27)28;/h6-7,10,14-16,18-21,23,25-26H,5,8-9,11-13H2,1-4H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,18+,19+,20-,21-,23-;/m0./s1

Molecular Formula	C24H37NaO6
Molar Mass	444.54
Melting Point	154-160°C
Boling Point	602.3°C at 760 mmHg
Flash Point	199.1°C
Solubility	Soluble in DMSO
Vapor Presure	5.09E-17mmHg at 25°C
Appearance	Solid powder
Storage Condition	Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Stability	Hygroscopic
In vitro study	Mevinolin in the hydroxy-acid form, mevinolinic acid, is a potent competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase [mevalonate: NADP + oxidoreductase (CoA-acylating)].